发明授权
US07973027B2 Compound with antimalarial activity and antimalarial drug containing the same as active ingredient
失效
具有抗疟活性的化合物和含有与活性成分相同的抗疟药
- 专利标题： Compound with antimalarial activity and antimalarial drug containing the same as active ingredient
- 专利标题（中）： 具有抗疟活性的化合物和含有与活性成分相同的抗疟药
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申请号： US12224387申请日： 2007-02-26
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公开(公告)号： US07973027B2公开(公告)日： 2011-07-05
- 发明人: Tsunehiko Higuchi , Hirohisa Omiya , Naoki Umezawa , Hye-Sook Kim , Yusuke Wataya
- 申请人： Tsunehiko Higuchi , Hirohisa Omiya , Naoki Umezawa , Hye-Sook Kim , Yusuke Wataya
- 申请人地址： JP Nagoya-shi
- 专利权人： Nagoya City University
- 当前专利权人： Nagoya City University
- 当前专利权人地址： JP Nagoya-shi
- 代理机构： Edwards Angell Palmer & Dodge LLP
- 优先权： JP2006-049678 20060227
- 国际申请： PCT/JP2007/053537 WO 20070226
- 国际公布： WO2007/097450 WO 20070830
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; C07D215/46
摘要：
Compounds with high antimalarial activity; and antimalarial drugs containing the same as an active ingredient. There are provided compounds with antimalarial activity represented by the chemical formula: (wherein R1 is H, Cl or OCH3; R2 is H or CH3; R3 is CH, CH2, C(CH3), CH(CH3) or C(CH3)2; Ar is imidazole, triazole, pyridine, benzene, pyrrole, furan, thiophene or derivatives thereof; n is 1 to 5; and m is 1 to 5). Further, there are provided antimalarial drugs containing these compounds with antimalarial activity or pharmacologically acceptable salts thereof as active ingredients.