发明授权
- 专利标题： Imidazole derivatives
- 专利标题（中）： 咪唑衍生物
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申请号： US11955421申请日： 2007-12-13
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公开(公告)号： US07973165B2公开(公告)日： 2011-07-05
- 发明人: Bernd Buettelmann , Simona Maria Ceccarelli , Georg Jaeschke , Sabine Kolczewski , Richard Hugh Philip Porter , Eric Vieira
- 申请人： Bernd Buettelmann , Simona Maria Ceccarelli , Georg Jaeschke , Sabine Kolczewski , Richard Hugh Philip Porter , Eric Vieira
- 申请人地址： US NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- 优先权： EP03012200 20030605
- 主分类号： C07D401/06
- IPC分类号： C07D401/06 ; C07D401/14
摘要：
The present invention relates to process for the preparation of an imidazole derivative of formula I, wherein R1, R2, R3 and R4 are described hereinabove. These compounds can be used in the treatment or prevention of mGluR5 receptor mediated disorders. These compounds are useful, inter alia, in the treatment or prevention of acute and/or chronic neurological disorders such as psychosis, epilepsy, schizophrenia, Alzheimer' disease, cognitive disorders and memory deficits, as well as chronic and acute pain.
公开/授权文献
- US20080103306A1 IMIDAZOLE DERIVATIVES 公开/授权日：2008-05-01
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