发明授权
US07976881B2 Combinations of vasoactive agents, their use in the pharmaceutical and cosmetic field, and formulations containing them
有权
血管活性剂的组合，它们在药物和化妆品领域的用途，以及含有它们的制剂
- 专利标题： Combinations of vasoactive agents, their use in the pharmaceutical and cosmetic field, and formulations containing them
- 专利标题（中）： 血管活性剂的组合，它们在药物和化妆品领域的用途，以及含有它们的制剂
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申请号： US10563965申请日： 2004-07-06
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公开(公告)号： US07976881B2公开(公告)日： 2011-07-12
- 发明人: Ezio Bombardelli
- 申请人： Ezio Bombardelli
- 申请人地址： IT Milan
- 专利权人： Indena S.p.A.
- 当前专利权人： Indena S.p.A.
- 当前专利权人地址： IT Milan
- 代理机构： Young & Thompson
- 优先权： ITMI2003A1427 20030711
- 国际申请： PCT/EP2004/007375 WO 20040706
- 国际公布： WO2005/004858 WO 20050120
- 主分类号： A61K36/16
- IPC分类号： A61K36/16 ; A61K36/00
摘要：
Combinations of vasoactive substances which act at venous or arterial level with phosphodiesterase inhibitors including phosphodiesterase V, in particular: visnadin or esculoside; at least one compound selected from icarin or derivatives thereof or extracts containing it, Gingko biloba dimeric flavones either in the free form or complexed with phospholipids, amentoflavone; at least one compound selected from escin, escin beta-sitosterol complexed with phospholipids, sericoside, sericoside complexed with phospholipids or Centella asiatica extract in the free form or complexed with phospholipids. The formulations are useful in reducing parmiculopathy and problems associated with venous insufficiency of the lower limbs.
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