A method for automatically removing a user from an e-mail thread is provided. An e-mail client receives a reply e-mail message. Responsive to a determination that the reply e-mail message is a message to opt-out of an e-mail thread, the e-mail address of a sender of the reply e-mail message is associated with the e-mail thread to form a listed e-mail address. The listed e-mail address is stored. When a new e-mail message is generated that is part of the e-mail thread, the listed e-mail address is automatically excluded from a list of recipients of the new e-mail.