发明授权
- 专利标题: 2-phenyl pyrimidines which are tubulin inhibitors
- 专利标题(中): 作为微管蛋白抑制剂的2-苯基嘧啶
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申请号: US10581534申请日: 2004-12-03
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公开(公告)号: US07981900B2公开(公告)日: 2011-07-19
- 发明人: Christopher John Burns , Andrew Frederick Wilks , Michael Francis Harte , Harrison Sikanyika , Emmanuelle Fantino
- 申请人: Christopher John Burns , Andrew Frederick Wilks , Michael Francis Harte , Harrison Sikanyika , Emmanuelle Fantino
- 申请人地址: AU Melbourne, Victoria
- 专利权人: YM Biosciences Australia Pty Ltd
- 当前专利权人: YM Biosciences Australia Pty Ltd
- 当前专利权人地址: AU Melbourne, Victoria
- 代理机构: Morrison & Foerster LLP
- 优先权: AU2003906680 20031203
- 国际申请: PCT/AU2004/001689 WO 20041203
- 国际公布: WO2005/054199 WO 20050616
- 主分类号: A01N43/54
- IPC分类号: A01N43/54
摘要:
Compounds of general formula (I), (II) (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
公开/授权文献
- US20080194583A1 Tubulin Inhibitors 公开/授权日:2008-08-14
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