发明授权
US07981905B2 Pharmaceutical formulations: salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-Ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same
有权
药物制剂：8 - [{1-（3,5-双 - （三氟甲基）苯基） - 乙氧基} - 甲基] -8-苯基-1,7-二氮杂 - 螺[4.5]癸-2-酮和 治疗方法使用相同
![Pharmaceutical formulations: salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-Ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same](/docs/US/2011-07-19/US07981905B2/abs.jpg.600x600.jpg)
- 专利标题： Pharmaceutical formulations: salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-Ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same
- 专利标题（中）： 药物制剂：8 - [{1-（3,5-双 - （三氟甲基）苯基） - 乙氧基} - 甲基] -8-苯基-1,7-二氮杂 - 螺[4.5]癸-2-酮和 治疗方法使用相同
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申请号： US12487263申请日： 2009-06-18
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公开(公告)号： US07981905B2公开(公告)日： 2011-07-19
- 发明人: Zhihui Qiu , Larisa Reyderman
- 申请人： Zhihui Qiu , Larisa Reyderman
- 申请人地址： US FL Miami
- 专利权人： OPKO Health, Inc.
- 当前专利权人： OPKO Health, Inc.
- 当前专利权人地址： US FL Miami
- 代理机构： Choate, Hall & Stewart LLP
- 代理商 Brenda Herschbach Jarrell; Kristen C. Buteau
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; C07D215/00 ; C07D491/00
![Pharmaceutical formulations: salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-Ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same](/abs-image/US/2011/07/19/US07981905B2/abs.jpg.150x150.jpg)
摘要：
Pharmaceutical formulations containing salts of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl]-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I, are disclosed. Disclosed also are methods of treatment utilizing such dosage forms.
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