发明授权
- 专利标题： Thio-substituted biarylmethanesulfinyl derivatives
- 专利标题（中）： 硫取代的联芳基甲亚磺酰基衍生物
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申请号： US12199167申请日： 2008-08-27
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公开(公告)号： US07981907B2公开(公告)日： 2011-07-19
- 发明人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , Marie-Edith Gourdel , Greg Hostetler , Mohamed Iqbal , Brigitte Lesur , Philippe Louvet , Eric Riguet , Dominique Schweizer , Christophe Yue
- 申请人： Edward R. Bacon , Sankar Chatterjee , Derek Dunn , Marie-Edith Gourdel , Greg Hostetler , Mohamed Iqbal , Brigitte Lesur , Philippe Louvet , Eric Riguet , Dominique Schweizer , Christophe Yue
- 申请人地址： US PA Frazer FR Maisons-Alfort Cedex
- 专利权人： Cephalon, Inc.,Cephalon France
- 当前专利权人： Cephalon, Inc.,Cephalon France
- 当前专利权人地址： US PA Frazer FR Maisons-Alfort Cedex
- 优先权： EP04290982 20040413
- 主分类号： A61K31/445
- IPC分类号： A61K31/445
摘要：
The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted biaryl-methanesulfinyl acetamides of Formula (I): wherein Ar, Y, R1, R2, R4, R5, q and x are as defined herein; and their use in the treatment of diseases, including treatment of sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work disorder; Parkinson's disease; Alzheimer's disease; attention deficit disorder; attention deficit hyperactivity disorder; depression; or fatigue associated with a neurological disease; as well as the promotion of wakefulness.
公开/授权文献
- US20090062284A1 Thio-Substituted Biarylmethanesulfinyl Derivatives 公开/授权日：2009-03-05