发明授权
- 专利标题： Compositions and methods for inhibiting gastric acid secretion
- 专利标题（中）： 抑制胃酸分泌的组合物和方法
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申请号： US12120599申请日： 2008-05-14
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公开(公告)号： US07981908B2公开(公告)日： 2011-07-19
- 发明人: Aleksey Kostadinov , David Ayelet , Sabina Glozman , Tal Atarot
- 申请人： Aleksey Kostadinov , David Ayelet , Sabina Glozman , Tal Atarot
- 申请人地址： IL Ra'annana
- 专利权人： Vecta, Ltd.
- 当前专利权人： Vecta, Ltd.
- 当前专利权人地址： IL Ra'annana
- 代理机构： Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- 代理商 Ivor R. Elrifi; Christina K. Stock, Esq.
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; A61K31/194
摘要：
The present invention is related to novel oral compositions comprising an irreversible gastric H+/K+-ATPase proton pump inhibitor (PPI) as a gastric acid secretion inhibitor and one or more small carboxylic acid molecules as parietal cell activators in the gastric lumen. Unexpectedly, the compositions of the present invention are capable of enhancing the anti-acid activity of PPI in the stomach. The present invention further relates to a method of using such compositions to reduce gastric acid secretion in a mammal.