发明授权
US07982003B2 Creating designer antimicrobials; peptidoglycan hydrolase module shuffling
失效
创造设计师抗菌药物; 肽聚糖水解酶模块洗牌
- 专利标题： Creating designer antimicrobials; peptidoglycan hydrolase module shuffling
- 专利标题（中）： 创造设计师抗菌药物; 肽聚糖水解酶模块洗牌
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申请号： US12498171申请日： 2009-07-06
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公开(公告)号： US07982003B2公开(公告)日： 2011-07-19
- 发明人: David M. Donovan
- 申请人： David M. Donovan
- 申请人地址： US DC Washington
- 专利权人： The United States of America as represented by the Secretary of Agriculture
- 当前专利权人： The United States of America as represented by the Secretary of Agriculture
- 当前专利权人地址： US DC Washington
- 代理商 John D. Fado; Evelyn M. Rabin
- 主分类号： C07K1/00
- IPC分类号： C07K1/00 ; C12N9/00 ; C12N9/14 ; C12N9/48 ; C12N9/52 ; A61K38/43
摘要：
The invention concerns a nucleic acid encoding a recombinant bifunctional fusion peptidoglycan hydrolase protein formed from a nucleic acid encoding a peptidoglycan hydrolase module and a nucleic acid encoding a second peptidoglycan hydrolase module. The fusion, dual (or multiples thereof) peptidoglycan hydrolase modules can be used to treat disease caused by the bacteria for which the individual modules of the fusion protein are specific.
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