发明授权
- 专利标题: Gastric juice-resistant device for releasing mucoadhesive active substance excipients, and method for producing this gastric juice-resistant device
- 专利标题(中): 用于释放粘膜粘附活性物质赋形剂的胃液装置及其制造方法
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申请号: US10475785申请日: 2002-04-22
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公开(公告)号: US07985427B2公开(公告)日: 2011-07-26
- 发明人: Despina Solomonidou , Markus Krumme , Bodo Asmussen , Joerg Kreuter
- 申请人: Despina Solomonidou , Markus Krumme , Bodo Asmussen , Joerg Kreuter
- 申请人地址: DE Andernach
- 专利权人: LTS Lohmann Therapie-Systeme AG
- 当前专利权人: LTS Lohmann Therapie-Systeme AG
- 当前专利权人地址: DE Andernach
- 代理机构: Birch, Stewart, Kolasch & Birch, LLP
- 优先权: DE10120092 20010425
- 国际申请: PCT/EP02/04381 WO 20020422
- 国际公布: WO02/085333 WO 20021031
- 主分类号: A61K9/16
- IPC分类号: A61K9/16 ; A61K9/20 ; A61K9/26 ; A61K9/24 ; A61K9/28 ; A61K9/34 ; A61K9/32 ; A61F13/00
摘要:
The invention relates to a gastric juice-resistant device for releasing active substance excipients having delayed intestinal passage from a gastric juice-resistant enclosure, and which serves to increase the active substance concentration in the intestines. The inventive device is characterized in that the active substance excipient containing at least one active substance is provided in the form of a multiparticulate preparation whose individual particles have mucoadhesive properties. The invention also relates to a method for producing said device.
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