发明授权
- 专利标题： Method of treating an IL-1 related coronary condition
- 专利标题（中）： 治疗IL-1相关冠状动脉疾病的方法
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申请号： US12464323申请日： 2009-05-12
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公开(公告)号： US07988968B2公开(公告)日： 2011-08-02
- 发明人: Linda Masat , Mary Haak-Frendscho , Arnold H. Horwitz , Gang Chen , Marina Roell
- 申请人： Linda Masat , Mary Haak-Frendscho , Arnold H. Horwitz , Gang Chen , Marina Roell
- 申请人地址： US CA Berkeley
- 专利权人： Xoma Technology Ltd.
- 当前专利权人： Xoma Technology Ltd.
- 当前专利权人地址： US CA Berkeley
- 代理机构： K&L Gates LLP
- 代理商 John Polo
- 主分类号： A61K39/395
- IPC分类号： A61K39/395
摘要：
An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 2, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.
公开/授权文献
- US20100055110A1 IL-1BETA BINDING ANTIBODIES AND FRAGMENTS THEREOF 公开/授权日：2010-03-04