Invention Grant
US07989622B2 Phosphatidylinositol 3-kinase inhibitors and methods of their use
有权
磷脂酰肌醇3-激酶抑制剂及其使用方法
- Patent Title: Phosphatidylinositol 3-kinase inhibitors and methods of their use
- Patent Title (中): 磷脂酰肌醇3-激酶抑制剂及其使用方法
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Application No.: US11988862Application Date: 2006-10-09
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Publication No.: US07989622B2Publication Date: 2011-08-02
- Inventor: William Bajjalieh , Lynne Canne Bannen , S. David Brown , Patrick Kearney , Morrison B. Mac , Charles K. Marlowe , John M. Nuss , Zerom Tesfai , Yong Wang , Wei Xu
- Applicant: William Bajjalieh , Lynne Canne Bannen , S. David Brown , Patrick Kearney , Morrison B. Mac , Charles K. Marlowe , John M. Nuss , Zerom Tesfai , Yong Wang , Wei Xu
- Applicant Address: US CA South San Francisco
- Assignee: Exelixis, Inc.
- Current Assignee: Exelixis, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Honigman Miller Schwartz & Cohn
- Agent Heidi M. Berven; Jonathan P. O'Brien
- International Application: PCT/US2006/039574 WO 20061009
- International Announcement: WO2007/044729 WO 20070419
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; A61K31/498 ; C07D241/36 ; C07D403/14 ; C07D471/04 ; A61P35/02 ; A61P35/00
Abstract:
The present invention comprises small molecule inhibitors of phosphatidylinositol 3-kinase (PI3K), which is associated with a number of malignancies such as ovarian cancer, cervical cancer, breast cancer, colon cancer, rectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases.
Public/Granted literature
- US20100087440A1 Phosphatidylinositol 3-Kinase Inhibitors and Methods of Their Use Public/Granted day:2010-04-08
Information query
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