发明授权
US07989663B2 Compounds and methods of use thereof for assaying lysophospholipase D activity
有权
用于测定溶血磷脂酶D活性的化合物及其使用方法
- 专利标题： Compounds and methods of use thereof for assaying lysophospholipase D activity
- 专利标题（中）： 用于测定溶血磷脂酶D活性的化合物及其使用方法
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申请号： US12290293申请日： 2008-10-28
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公开(公告)号： US07989663B2公开(公告)日： 2011-08-02
- 发明人: Colin Ferguson , Glenn Prestwich
- 申请人： Colin Ferguson , Glenn Prestwich
- 申请人地址： US UT Salt Lake City
- 专利权人： Echelon Biosciences Incorporated
- 当前专利权人： Echelon Biosciences Incorporated
- 当前专利权人地址： US UT Salt Lake City
- 代理机构： The McCallum Law Firm, P.C.
- 代理商 Jennifer M. McCallum, Esq.
- 主分类号： C07F9/02
- IPC分类号： C07F9/02
摘要：
Fluorogenic lysophosphatidic acid derivatives which can be used as substrates in a continuous, fluorogenic assay that can be performed in microtiter plates. The assays permit measuring LysoPLD activity levels in normal events such as pregnancy or disease states such as cancer. In addition, the present invention can be adopted to high throughout screening (HTS) for identification of potential inhibitors of lysoPLD activity.
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