Invention Grant
US07991601B2 Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, crystalline form of same, and screening methods employing same
失效
分离的GRP94配体结合域多肽和编码相同的核酸，结晶形式相同，以及使用其的筛选方法
- Patent Title: Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, crystalline form of same, and screening methods employing same
- Patent Title (中): 分离的GRP94配体结合域多肽和编码相同的核酸，结晶形式相同，以及使用其的筛选方法
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Application No.: US12754423Application Date: 2010-04-05
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Publication No.: US07991601B2Publication Date: 2011-08-02
- Inventor: Daniel T. Gewirth , Christopher V. Nicchitta
- Applicant: Daniel T. Gewirth , Christopher V. Nicchitta
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- Main IPC: G06G7/58
- IPC: G06G7/58 ; G01N23/00
Abstract:
An isolated GRP94 ligand binding domain polypeptide, a three-dimensional crystal structure of the same, and methods of using the same to design modulators of Hsp90 proteins.
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