发明授权
- 专利标题: HPRP4s modifiers of the p53 pathway and methods of use
- 专利标题(中): HPRP4s p53途径的修饰和使用方法
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申请号: US11627831申请日: 2007-01-26
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公开(公告)号: US07993829B2公开(公告)日: 2011-08-09
- 发明人: Lori Friedman , Gregory D. Plowman , Tak Hung , Helen Francis-Lang , Danix Li , Roel P. Funke , Michael Costa
- 申请人: Lori Friedman , Gregory D. Plowman , Tak Hung , Helen Francis-Lang , Danix Li , Roel P. Funke , Michael Costa
- 申请人地址: US CA South San Francisco
- 专利权人: Exelixis Inc.
- 当前专利权人: Exelixis Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理机构: McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
Human hPRP4 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of hPRP4 are provided.
公开/授权文献
- US20070160539A1 HPRP4s Modifiers of the p53 Pathway and Methods of Use 公开/授权日:2007-07-12