A system and method facilitate alignment of refill dates associated with a plurality of prescriptions, such that each of the plurality of prescriptions requires a refill on the same date, thus limiting the number of occasions on which a customer must visit the pharmacy to retrieve refills of the aligned prescriptions, and increasing the likelihood that the customer will comply with the prescribed medication regimen. The system and method facilitate the alignment of the refill dates while complying with one or more rules governing the adjudication of the prescriptions.