A scrub brush-sponge includes a base provided with a recessed peripheral lip, which has a plurality of attenuated regions configured to minimize the resistance of the base to external bending forces, and a sponge coupled to the base and made from polymeric material, which may have as low a PPI as 10. The sponge is configured so that it can effectively surround at least a substantial peripheral portion of instruments or portions to be treated with fluid, which is contained within the sponge, without applying substantial external forces to the base. A flexible layer made of woven or non-woven bonded polymeric fibers is on a scrubbing surface of the sponge and provides an enhanced scrubbing feature. An abrasive may be included on the flexible layer to further enhance the scrubbing feature.