发明授权
- 专利标题： Pyrrolopyrazine kinase inhibitors
- 专利标题（中）： 吡咯吡嗪激酶抑制剂
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申请号： US12378977申请日： 2009-02-20
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公开(公告)号： US08008298B2公开(公告)日： 2011-08-30
- 发明人: Joe Timothy Bamberg , Daisy Joe DuBois , Todd Richard Elworthy , Robert Than Hendricks , Johannes Cornelius Hermann , Alam Jahangir , Rama K. Kondru , Remy Lemoine , Yan Lou , Timothy D. Owens , David Bernard Smith , Michael Soth , Hanbiao Yang
- 申请人： Joe Timothy Bamberg , Daisy Joe DuBois , Todd Richard Elworthy , Robert Than Hendricks , Johannes Cornelius Hermann , Alam Jahangir , Rama K. Kondru , Remy Lemoine , Yan Lou , Timothy D. Owens , David Bernard Smith , Michael Soth , Hanbiao Yang
- 申请人地址： US CA Palo Alto
- 专利权人： Roche Palo Alto
- 当前专利权人： Roche Palo Alto
- 当前专利权人地址： US CA Palo Alto
- 代理商 George W. Johnston; Dennis P. Tramaloni; Jennifer Kisko
- 主分类号： A61K31/495
- IPC分类号： A61K31/495
摘要：
The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables Q1, R, and X are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
公开/授权文献
- US20100267666A1 Pyrrolopyrazine kinase inhibitors 公开/授权日：2010-10-21