发明授权
US08008313B2 Methods of using diaminopyrimidine P2X3 and P2X2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases
有权
使用二氨基嘧啶P2X3和P2X2 / 3受体调节剂治疗呼吸道和胃肠道疾病的方法
- 专利标题： Methods of using diaminopyrimidine P2X3 and P2X2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases
- 专利标题（中）： 使用二氨基嘧啶P2X3和P2X2 / 3受体调节剂治疗呼吸道和胃肠道疾病的方法
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申请号： US11509921申请日： 2006-08-25
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公开(公告)号： US08008313B2公开(公告)日： 2011-08-30
- 发明人: Chris Allen Broka , David Scott Carter , Michael Patrick Dillon , Anthony P. D. W. Ford , Ronald Charles Hawley , Alam Jahangir , Amy Geraldine Moore , Daniel Warren Parish
- 申请人： Chris Allen Broka , David Scott Carter , Michael Patrick Dillon , Anthony P. D. W. Ford , Ronald Charles Hawley , Alam Jahangir , Amy Geraldine Moore , Daniel Warren Parish
- 申请人地址： US CA Palo Alto
- 专利权人： Roche Palo Alto LLC
- 当前专利权人： Roche Palo Alto LLC
- 当前专利权人地址： US CA Palo Alto
- 代理商 Robert C. Hall
- 主分类号： A61K31/505
- IPC分类号： A61K31/505
摘要：
Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.
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