发明授权
- 专利标题: Treatment of colorectal polyps with imidazoquinoline derivatives
- 专利标题(中): 用咪唑并喹啉衍生物治疗结肠直肠息肉
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申请号: US12353683申请日: 2009-01-14
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公开(公告)号: US08008319B2公开(公告)日: 2011-08-30
- 发明人: Joachim Maus , Istvan Szelenyi , Ursula Petzold
- 申请人: Joachim Maus , Istvan Szelenyi , Ursula Petzold
- 申请人地址: DE Homburg
- 专利权人: Meda Pharma GmbH & Co. KG
- 当前专利权人: Meda Pharma GmbH & Co. KG
- 当前专利权人地址: DE Homburg
- 代理机构: Venable LLP
- 代理商 Keith G. Haddaway
- 主分类号: A61K31/4745
- IPC分类号: A61K31/4745 ; A61K31/4375
摘要:
The invention relates to treating colorectal polyps and precancercerous colorectal changes by topical administration of immunomodulating drugs of the imidazoquinoline family, such as imiquimod (1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine), resiquimod (4-amino-α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol), sotirimod (2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine).
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