Invention Grant
US08012486B2 Composition for treating atopic dermatitis comprising hirsutenone as an active ingredient
有权
用于治疗特应性皮炎的组合物，其包含以高分子量酮为活性成分
- Patent Title: Composition for treating atopic dermatitis comprising hirsutenone as an active ingredient
- Patent Title (中): 用于治疗特应性皮炎的组合物，其包含以高分子量酮为活性成分
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Application No.: US12454520Application Date: 2009-05-19
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Publication No.: US08012486B2Publication Date: 2011-09-06
- Inventor: Min Won Lee , Young Wook Choi , Seong Jun Seo , Do Ik Lee , Hyoweon Bang , Chung Soo Lee , Jong Chan Lee , Soon-Chul Myung , Mi-Kyung Lee , Seong Soo Joo , Sun Eun Choi
- Applicant: Min Won Lee , Young Wook Choi , Seong Jun Seo , Do Ik Lee , Hyoweon Bang , Chung Soo Lee , Jong Chan Lee , Soon-Chul Myung , Mi-Kyung Lee , Seong Soo Joo , Sun Eun Choi
- Applicant Address: KR Seoul
- Assignee: Chung-Ang University Industry Academic Cooperation Foundation
- Current Assignee: Chung-Ang University Industry Academic Cooperation Foundation
- Current Assignee Address: KR Seoul
- Agency: Clark & Elbing LLP
- Priority: KR10-2009-0006646 20090128
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K8/02 ; A61K47/00 ; A61K31/12
Abstract:
The present invention relates to a composition for treating atopic dermatitis comprising hirsutenone as an active ingredient. Hirsutenone as the active ingredient of the present composition decreases the number of eosinophil and the level of IgE increased in atopic dermatitis and remarkably reduces expression amounts of immune regulatory cytokine (e.g., IL-4, IL-5 and IL-13) associated with atopic dermatitis. In addition, hirsutenone decreases COX-2 and iNOS expression. Hirsutenone as the active ingredient of the present composition could be effectively used in drugs, cosmetics and foods for treating atopic dermatitis or relieving a symptom of atopic dermatitis.
Public/Granted literature
- US20100190862A1 Composition for treating atopic dermatitis comprising hirsutenone as an active ingredient Public/Granted day:2010-07-29
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