发明授权
- 专利标题： Phosphodiesterase and gene thereof
- 专利标题（中）： 磷酸二酯酶及其基因
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申请号： US11960999申请日： 2007-12-20
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公开(公告)号： US08012731B2公开(公告)日： 2011-09-06
- 发明人: Kenji Omori , Keizo Yuasa , Jun Kotera , Kotomi Oda , Hideo Michibata
- 申请人： Kenji Omori , Keizo Yuasa , Jun Kotera , Kotomi Oda , Hideo Michibata
- 申请人地址： JP Osaka
- 专利权人： Tanabe Seiyaku Co., Ltd.
- 当前专利权人： Tanabe Seiyaku Co., Ltd.
- 当前专利权人地址： JP Osaka
- 代理机构： Browdy and Neimark PLLC
- 优先权： JP11-364866 19991222; JP2000-163875 20000601
- 主分类号： C07H21/00
- IPC分类号： C07H21/00 ; C12N15/00 ; C12Q1/68 ; C12N1/21 ; C12N5/10 ; C12N9/16 ; C12P21/00
摘要：
The present invention is to provide a novel phosphodiesterase and a gene thereof, specifically, Type 11 phosphodiesterase (PDE11) and a gene thereof, more specifically, a phosphodiesterase selected from (A) a protein having an amino acid sequenced shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39, and (B) a protein having an amino acid sequence shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39 in which one or several amino acids are deleted, substituted or added, and having an activity of hydrolyzing a cyclic nucleotide, and a gene thereof, and a method of characterizing, identifying and selecting a phosphodiesterase inhibitor by using the same.
公开/授权文献
- US20090325207A1 NOVEL PHOSPHODIESTERASE AND GENE THEREOF 公开/授权日：2009-12-31