发明授权
- 专利标题： Preparation of rivastigmine and its salts
- 专利标题（中）： 制备利凡斯的明及其盐
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申请号： US12100591申请日： 2008-04-10
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公开(公告)号： US08013181B2公开(公告)日： 2011-09-06
- 发明人: Venkata Naga Brahmeswara Rao Mandava , Venkata Reddy Vajrala , Ganesh Varanasi , Vijay Kumar Adla , Mukund Reddy Jambula , Vijaypal Reddy Kanumathi Reddy
- 申请人： Venkata Naga Brahmeswara Rao Mandava , Venkata Reddy Vajrala , Ganesh Varanasi , Vijay Kumar Adla , Mukund Reddy Jambula , Vijaypal Reddy Kanumathi Reddy
- 申请人地址： IN Hyderabad US NJ Bridgewater
- 专利权人： Dr. Reddy's Laboratories Limited,Dr. Reddy's Laboratories, Inc.
- 当前专利权人： Dr. Reddy's Laboratories Limited,Dr. Reddy's Laboratories, Inc.
- 当前专利权人地址： IN Hyderabad US NJ Bridgewater
- 代理商 Thomas C. McKenzie; Balaram Gupta; Robert A. Franks
- 优先权： IN758/CHE/2007 20070410
- 主分类号： C07C269/00
- IPC分类号： C07C269/00
摘要：
There are provided processes for making rivastigmine. In one embodiment, the process includes reacting S-(−)-[1-(3-hydroxyphenyl)ethyl]dimethylamine with N-ethyl-N-methyl carbamoyl chloride in the presence of an organic base to obtain a free base of rivastigmine.
公开/授权文献
- US20080255383A1 PREPARATION OF RIVASTIGMINE AND ITS SALTS 公开/授权日：2008-10-16
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