发明授权
- 专利标题： Imidazopyridines
- 专利标题（中）： 咪唑并吡啶
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申请号： US12886657申请日： 2010-09-21
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公开(公告)号： US08017604B2公开(公告)日： 2011-09-13
- 发明人: Daniela Alberati , Rubén Alvarez Sánchez , Konrad Bleicher , Alexander Flohr , Katrin Groebke Zbinden , Matthias Koerner , Bernd Kuhn , Jens-Uwe Peters , Markus Rudolph
- 申请人： Daniela Alberati , Rubén Alvarez Sánchez , Konrad Bleicher , Alexander Flohr , Katrin Groebke Zbinden , Matthias Koerner , Bernd Kuhn , Jens-Uwe Peters , Markus Rudolph
- 申请人地址： US NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- 优先权： EP09171253 20090924
- 主分类号： A61K31/535
- IPC分类号： A61K31/535 ; A61K31/44 ; A01N43/42 ; C07D491/02 ; C07D498/02 ; C07D413/00
摘要：
The invention is concerned with novel imidazopyridine derivatives of formula (I) wherein R1, R2, R3, R4, R5 and A are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDE10A and can be used for the treatment of various diseases, including central nervous system disorders such as Alzheimer's disease, Parkinson's disease, and schizophrenia.
公开/授权文献
- US20110071128A1 NOVEL IMIDAZOPYRIDINES 公开/授权日：2011-03-24
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