发明授权
- 专利标题： Oxadiazole derivatives and their medical use
- 专利标题（中）： 恶二唑衍生物及其医疗用途
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申请号： US11919146申请日： 2006-04-24
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公开(公告)号： US08017631B2公开(公告)日： 2011-09-13
- 发明人: Bjarne H. Dahl , Dan Peters , Gunnar M. Olsen , Daniel B. Timmermann , Susanne Jørgensen
- 申请人： Bjarne H. Dahl , Dan Peters , Gunnar M. Olsen , Daniel B. Timmermann , Susanne Jørgensen
- 申请人地址： DK Ballerup
- 专利权人： Neurosearch A/S
- 当前专利权人： Neurosearch A/S
- 当前专利权人地址： DK Ballerup
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： DK200500612 20050426
- 国际申请： PCT/EP2006/061773 WO 20060424
- 国际公布： WO2006/114400 WO 20061102
- 主分类号： A61K31/4245
- IPC分类号： A61K31/4245 ; C07D413/04
摘要：
This invention relates to novel oxadiazole derivatives, which are found to be modulators of the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
公开/授权文献
- US20090312347A1 Novel oxadiazole derivatives and their medical use 公开/授权日：2009-12-17