发明授权
- 专利标题: Glucokinase activators
- 专利标题(中): 葡萄糖激酶激活剂
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申请号: US12161366申请日: 2007-01-24
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公开(公告)号: US08022222B2公开(公告)日: 2011-09-20
- 发明人: Thomas D. Aicher , Steven Armen Boyd , Mark Joseph Chicarelli , Kevin Ronald Condroski , Rustam Ferdinand Garrey , Ronald Jay Hinklin , Ajay Singh , Timothy M. Turner
- 申请人: Thomas D. Aicher , Steven Armen Boyd , Mark Joseph Chicarelli , Kevin Ronald Condroski , Rustam Ferdinand Garrey , Ronald Jay Hinklin , Ajay Singh , Timothy M. Turner
- 申请人地址: US CO Boulder
- 专利权人: Array Biopharma, Inc.
- 当前专利权人: Array Biopharma, Inc.
- 当前专利权人地址: US CO Boulder
- 代理机构: Banner & Witcoff, Ltd.
- 国际申请: PCT/US2007/001956 WO 20070124
- 国际公布: WO2007/089512 WO 20070809
- 主分类号: C07D417/00
- IPC分类号: C07D417/00 ; A61K31/44
摘要:
Provided are compounds of formula I wherein R2, L, Z, Y, G and R1 are as defined herein, that are useful in the treatment and/or prevention of diseases or disorders mediated by deficient levels of glucokinase activity or which can be treated by activating glucokinase including, but not limited to, diabetes mellitus, impaired glucose tolerance, IFG (impaired fasting glucose) and IFG (impaired fasting glycemia), as well as other diseases and disorders such as those discussed herein.
公开/授权文献
- US20090247526A1 GLUCOKINASE ACTIVATORS 公开/授权日:2009-10-01