A multi-gas/gas-mixture or liquid flow sensor apparatus utilizing a specific media calibration capability. The flow sensor can be coupled with an Application Specific Integrated Circuit (ASIC) that incorporates a signal conditioner and a memory module. The signal conditioner provides a high order calibration and signal processing of flow signals from the sensor to a processed signal output representative of the flow. The processed signal output can be stored in the memory module. A correction factor can be calculated and stored in the memory module in response to the stored values of the processed signal output, which tends to linearize the relationship between the flow rate and the processed signal output of a measuring system. The correction factor and/or the processed signal output provided by the signal conditioner can be utilized by the measuring system.