发明授权
US08026223B1 Treating malignant tumors with high field strength electroporation of plasmids encoding IL-12
有权
用编码IL-12的质粒的高场强电穿孔治疗恶性肿瘤
- 专利标题: Treating malignant tumors with high field strength electroporation of plasmids encoding IL-12
- 专利标题(中): 用编码IL-12的质粒的高场强电穿孔治疗恶性肿瘤
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申请号: US11164626申请日: 2005-11-30
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公开(公告)号: US08026223B1公开(公告)日: 2011-09-27
- 发明人: Richard Heller , Melinda Lee Lucas
- 申请人: Richard Heller , Melinda Lee Lucas
- 申请人地址: US FL Tampa
- 专利权人: University of South Florida
- 当前专利权人: University of South Florida
- 当前专利权人地址: US FL Tampa
- 代理机构: Smith & Hopen, P.A.
- 代理商 Molly L. Sauter
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C12N15/87
摘要:
In accordance with the present invention is provided a method of treating a subject having a cancerous tumor. The treatment protocol methodology includes injecting the cancerous tumor with an effective dose of plasmid coding for a therapeutic protein followed by administering electroporation therapy to the tumor, the electroporation therapy includes the administration of at least one high voltage, short duration pulse to the tumor.
公开/授权文献
- US1716606A Furfural reaction product 公开/授权日:1929-06-11
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