发明授权
US08030274B2 Method for treating asthma and chronic obstructive pulmonary disease (COPD) comprising administering FGF2
有权
治疗哮喘和慢性阻塞性肺疾病（COPD）的方法，包括给予FGF2
- 专利标题： Method for treating asthma and chronic obstructive pulmonary disease (COPD) comprising administering FGF2
- 专利标题（中）： 治疗哮喘和慢性阻塞性肺疾病（COPD）的方法，包括给予FGF2
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申请号： US11568896申请日： 2005-05-12
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公开(公告)号： US08030274B2公开(公告)日： 2011-10-04
- 发明人: Yoon-Keum Kim , Soo Hyung Kang , Byong Moon Kim , Miwon Son
- 申请人： Yoon-Keum Kim , Soo Hyung Kang , Byong Moon Kim , Miwon Son
- 申请人地址： KR Seoul
- 专利权人： Dong-A Pharmaceutical Co., Ltd.
- 当前专利权人： Dong-A Pharmaceutical Co., Ltd.
- 当前专利权人地址： KR Seoul
- 代理机构： Lucas & Mercanti, LLP
- 优先权： KR10-2004-0033261 20040512
- 国际申请： PCT/KR2005/001390 WO 20050512
- 国际公布： WO2005/107794 WO 20051117
- 主分类号： A61K38/18
- IPC分类号： A61K38/18 ; C07K14/50
摘要：
The present invention relates an agent comprising FGF2 (Fibroblast Growth Factor-2 or basic Fibroblast Growth Factor (bFGF)) as an effective ingredient for treatment or prevention of Asthma and Chronic Obstructive Pulmonary Disease (COPD). Also, The present invention relates Th1 asthma and COPD mouse animal model induced by Ovalbumin and double strand RNA. The therapeutic agent comprising FGF2 of the present invention can be used for treatment or prevention for airway fibrosis, airway inflammation, airway hyperresponsiveness, airway remodeling, asthma and COPD. Also, Th1 asthma and COPD mice animal model induced by Ovalbumin and double strand RNA can be used for development of therapeutic agent for asthma and COPD.
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