发明授权
US08030341B2 Dmt-derivative compounds and related compositions and methods of use
失效
Dmt衍生化合物及相关组合物和使用方法
- 专利标题： Dmt-derivative compounds and related compositions and methods of use
- 专利标题（中）： Dmt衍生化合物及相关组合物和使用方法
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申请号： US12065121申请日： 2006-08-30
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公开(公告)号： US08030341B2公开(公告)日： 2011-10-04
- 发明人: Lawrence H. Lazarus , Yoshio Okada , Tingyou Li
- 申请人： Lawrence H. Lazarus , Yoshio Okada , Tingyou Li
- 申请人地址： US DC Washington JP Kobe
- 专利权人： The United States of America as represented by the Secretary of the Department of Health and Human Services,Kobe Gakuin University
- 当前专利权人： The United States of America as represented by the Secretary of the Department of Health and Human Services,Kobe Gakuin University
- 当前专利权人地址： US DC Washington JP Kobe
- 代理机构： Leydig, Voit & Mayer, Ltd.
- 国际申请： PCT/US2006/033560 WO 20060830
- 国际公布： WO2007/027628 WO 20070308
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; A61K31/4725
摘要：
The present invention relates to symmetric and asymmetric dimeric Dmt (2′,6′-ditnethyl) compounds and Dmt derivative compounds with dual δ and μ opioid receptor antagonist activity. Also, the present invention provides compositions comprising these compounds and it provides methods of using these compounds.
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