- 专利标题: CCR9 inhibitors and methods of use thereof
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申请号: US12630040申请日: 2009-12-03
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公开(公告)号: US08030517B2公开(公告)日: 2011-10-04
- 发明人: Paul E. Fleming , Geraldine C. B. Harriman , Zhan Shi , B. Shaowu Chen
- 申请人: Paul E. Fleming , Geraldine C. B. Harriman , Zhan Shi , B. Shaowu Chen
- 申请人地址: US MA Cambridge
- 专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Cambridge
- 主分类号: C07C311/15
- IPC分类号: C07C311/15 ; C07D213/02 ; A61K31/18 ; A61K31/44 ; A61K31/50 ; A61P1/00 ; A61P29/00
摘要:
The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds represented by Structural Formula I in research, therapeutic, prophylactic and diagnostic methods.
公开/授权文献
- US20100280074A1 CCR9 INHIBITORS AND METHODS OF USE THEREOF 公开/授权日:2010-11-04
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