Invention Grant
- Patent Title: Method of delivery of nucleic acids to peripheral neurons
- Patent Title (中): 向周围神经元递送核酸的方法
-
Application No.: US11795348Application Date: 2005-01-20
-
Publication No.: US08034331B2Publication Date: 2011-10-11
- Inventor: Shu Wang , Xu Wang
- Applicant: Shu Wang , Xu Wang
- Applicant Address: SG Singapore
- Assignee: Agency for Science, Technology and Research
- Current Assignee: Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/SG2005/000015 WO 20050120
- International Announcement: WO2006/078221 WO 20060727
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A01N63/00
Abstract:
The invention provides for methods for delivering a nucleic acid into a peripheral neuron by identifying a target neuron in a dorsal root ganglion and intrathecally delivering a vector comprising the nucleic acid to the dorsal root ganglion neuron. The nucleic acid may encode a neurotrophic factor that may be used to treat a peripheral neuropathy or, in conjunction with a nerve guide conduit, to treat a transected peripheral nerve.
Public/Granted literature
- US20080318882A1 Method of Delivery of Nucleic Acids to Peripheral Neurons Public/Granted day:2008-12-25
Information query
