发明授权
- 专利标题: Glycolipids and synthetic method thereof as well as their synthetic intermediates, and synthetic method thereof
- 专利标题(中): 糖脂及其合成方法及其合成中间体及其合成方法
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申请号: US12760793申请日: 2010-04-15
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公开(公告)号: US08034908B2公开(公告)日: 2011-10-11
- 发明人: Hirokazu Annoura , Kenji Murata , Takashi Yamamura
- 申请人: Hirokazu Annoura , Kenji Murata , Takashi Yamamura
- 申请人地址: JP Kodaira-shi, Tokyo
- 专利权人: Japan as Represented by President of National Center of Neurology and Psychiatry
- 当前专利权人: Japan as Represented by President of National Center of Neurology and Psychiatry
- 当前专利权人地址: JP Kodaira-shi, Tokyo
- 代理机构: Drinker Biddle & Reath LLP
- 优先权: JP2003-037397 20030214
- 主分类号: C07J9/00
- IPC分类号: C07J9/00 ; C07H17/02 ; A01N43/04 ; A61K31/70
摘要:
Novel glycolipid derivatives, where the substituent of the sphingosine base part is a short carbon chain alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aralkyl group and efficient synthetic methods for practical mass production of the same and intermediates useful for the synthesis of these compounds.Glycolipids having the formula (I): where R3 indicates a substituted or unsubstituted C1 to C7 linear alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted aryl group, or substituted or unsubstituted aralkyl group and R8 indicates a substituted or unsubstituted C1 to C35 alkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aralkyl group are chemically synthesized.
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