Certain aspects of a method and system for independent in-phase (I) and quadrature (Q) loop amplitude control for quadrature generators may include determining an amplitude voltage associated with an in-phase (I) component and a quadrature (Q) component of a generated signal. A DC reference voltage associated with the I component and the Q component may be determined. The determined amplitude voltage may be compared with the determined reference voltage to generate a control signal. The amplitude mismatch between the I component and the Q component may be compensated by controlling a biasing current of one or more programmable buffers associated with one or both of the I component and the Q component, based on the generated control signal.