发明授权
- 专利标题： Method for discrimination of metaplasias from neoplastic or preneoplastic lesions
- 专利标题（中）： 从肿瘤或肿瘤前病变中鉴别化生的方法
-
申请号： US12164934申请日： 2008-06-30
-
公开(公告)号： US08043819B2公开(公告)日： 2011-10-25
- 发明人: Ruediger Ridder , Magnus Von Knebel Doeberitz , Peter Martin
- 申请人： Ruediger Ridder , Magnus Von Knebel Doeberitz , Peter Martin
- 申请人地址： DE Heidelberg
- 专利权人： mtm Laboratories, AG
- 当前专利权人： mtm Laboratories, AG
- 当前专利权人地址： DE Heidelberg
- 代理机构： Fitzpatrick, Cella, Harper & Scinto
- 优先权： EP02007954 20020409
- 主分类号： G01N33/53
- IPC分类号： G01N33/53
摘要：
The present invention relates to a method for discrimination of p16INK4a overexpressing metaplasias from neoplastic or preneoplastic p16INK4a overexpressing lesions by determination of the level of high risk HPV encoded gene-products such as e.g. HPV E2 and/or HPV E7 molecules in biological samples in the course of cytological testing procedures. The method thus enables for reduction of false positive results in the p16INK4a based detection of anogenital lesions in cytological testing procedures.
公开/授权文献
信息查询
IPC分类:
