A self-cleansing portable urine collection device and method of collecting urine in a self-cleansing portable urine collection device is provided. The collection device includes a housing which houses a urine collection receptacle configured to collect urine from a user. A cleansing container which retains a cleansing solution is configured to supply the cleansing solution to the receptacle. The device further includes a reservoir coupled to the receptacle and configured to receive the urine and the cleansing solution collected by the receptacle. A pump coupled to the receptacle and the reservoir is configured to transport the urine and the cleansing solution from the receptacle to the reservoir.