A method and apparatus for suppressing a transmit leakage signal of a radio frequency identification (RFID) reader is provided. The apparatus includes: a first power distributor distributing a transmission signal to output a first transmission signal and a second transmission signal; a second power distributor distributing the second transmission signal to output a third transmission signal and a fourth transmission signal; a first amplitude/phase converter converting an amplitude and a phase of the first transmission signal to generate a first converted signal; a second amplitude/phase converter converting an amplitude and a phase of the third transmission signal to generate a second converted signal; a first power combiner combining the first converted signal with a first leakage signal generated in association with the fourth transmission signal; and a second power combiner combining the second converted signal with a second leakage signal generated in association with the fourth transmission signal.