An applicator directly delivers one or more active ingredients, such as flea, tick, or insect repellant to an animal's skin. The applicator comprises an applicator base connected to an applicator head having at least on prong member constructed with an internal channel therein in communication with a delivery aperture. A separately presented cartridge having a solution tube is appointed to be removably received within the applicator's base which, in turn is uniquely sized and shaped to receive a preselected one of those cartridges currently sold under recognized medicament brands. As the cartridge is squeezed, the solution traverses from the cartridge and applicator base into the applicator head and through the internal channels of the prong members, exiting through the delivery apertures onto the animal. Improved delivery owing to the prong members with channels therein terminating at fine delivery apertures is provided to yield direct delivery of the solution onto the animal's skin local to the fur shafts for a clean application and accurate dispersion of solution onto the animal.