发明授权
- 专利标题： Polycyclic antagonists of lysophosphatidic acid receptors
- 专利标题（中）： 溶血磷脂酸受体的多环拮抗剂
-
申请号： US12793440申请日： 2010-06-03
-
公开(公告)号： US08058300B2公开(公告)日： 2011-11-15
- 发明人: John Howard Hutchinson , Thomas Jon Seiders , Bowei Wang , Jeannie M. Arruda , Jeffrey Roger Roppe , Timothy Parr
- 申请人： John Howard Hutchinson , Thomas Jon Seiders , Bowei Wang , Jeannie M. Arruda , Jeffrey Roger Roppe , Timothy Parr
- 申请人地址： US CA San Diego
- 专利权人： Amira Pharmaceuticals, Inc.
- 当前专利权人： Amira Pharmaceuticals, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Wilson Sonsini Goodrich & Rosati
- 主分类号： A61K31/42
- IPC分类号： A61K31/42 ; C07D261/14
摘要：
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.