发明授权
- 专利标题: Method for producing mature VWF from VWF pro-peptide
- 专利标题(中): 从VWF前肽生产成熟VWF的方法
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申请号: US12152762申请日: 2008-05-16
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公开(公告)号: US08058411B2公开(公告)日: 2011-11-15
- 发明人: Wolfgang Mundt , Artur Mitterer , Meinhard Hasslacher , Christa Mayer
- 申请人: Wolfgang Mundt , Artur Mitterer , Meinhard Hasslacher , Christa Mayer
- 申请人地址: US IL Deerfield CH Glattpark (Opfikon)
- 专利权人: Baxter International Inc.,Baxter Healthcare S.A.
- 当前专利权人: Baxter International Inc.,Baxter Healthcare S.A.
- 当前专利权人地址: US IL Deerfield CH Glattpark (Opfikon)
- 代理机构: Marshall, Gerstein & Borun LLP
- 主分类号: C07K1/18
- IPC分类号: C07K1/18 ; C07K17/00 ; A61K35/16
摘要:
The present invention relates to a method for producing a mature von Willebrand Factor (VWF) from von Willebrand Factor pro-peptide comprising the steps: immobilizing VWF pro-peptide on an ion exchange resin, incubating the immobilized VWF pro-peptide with furin to obtain immobilized mature VWF, and isolating mature VWF from the ion exchange resin by elution.
公开/授权文献
- US20090029918A1 Method for producing mature VWF from VWF Pro-Peptide 公开/授权日:2009-01-29
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