发明授权
- 专利标题： Eszopiclone process
- 专利标题（中）： 异佐布龙过程
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申请号： US12339253申请日： 2008-12-19
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公开(公告)号： US08058438B2公开(公告)日： 2011-11-15
- 发明人: Venkata Naga Brahmeswara Rao Mandava , Sreenadhacharyulu Kandala , Mukunda Reddy Jambula , Raveendra Reddy Chinta
- 申请人： Venkata Naga Brahmeswara Rao Mandava , Sreenadhacharyulu Kandala , Mukunda Reddy Jambula , Raveendra Reddy Chinta
- 申请人地址： IN Hyderabad, Andhra Pradesh US NJ Bridgewater
- 专利权人： Dr. Reddy's Laboratories Limited,Dr. Reddy's Laboratories, Inc.,
- 当前专利权人： Dr. Reddy's Laboratories Limited,Dr. Reddy's Laboratories, Inc.,
- 当前专利权人地址： IN Hyderabad, Andhra Pradesh US NJ Bridgewater
- 代理商 Robert A. Franks; Balaram Gupta; Thomas C. McKenzie
- 优先权： IN1241/CHE/2005 20050905; IN1806/CHE/2005 20051209; IN1064/CHE/2006 20060622
- 主分类号： C07D487/02
- IPC分类号： C07D487/02
摘要：
Eszopiclone is prepared by reacting zopiclone with an enatiomerically pure di-p-toluoyl tartaric acid, recovering a solid salt, and reacting a solid salt with a base. Zopiclone is prepared by reacting 6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]-pyrazine with 1-chlorocarbonyl-4-methylpiperazine hydrochloride.
公开/授权文献
- US20090099359A1 ESZOPICLONE PROCESS 公开/授权日：2009-04-16
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