发明授权
- 专利标题： Substituted pyridone compounds and methods of use
- 专利标题（中）： 取代的吡啶酮化合物和使用方法
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申请号： US12711167申请日： 2010-02-23
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公开(公告)号： US08063055B2公开(公告)日： 2011-11-22
- 发明人: Essa Hu , Jason Brooks Human , Roxanne Kunz , Andrew Tasker , Ryan White
- 申请人： Essa Hu , Jason Brooks Human , Roxanne Kunz , Andrew Tasker , Ryan White
- 申请人地址： US CA Thousand Oaks
- 专利权人： Amgen Inc.
- 当前专利权人： Amgen Inc.
- 当前专利权人地址： US CA Thousand Oaks
- 代理商 G. Prabhakar Reddy
- 主分类号： A61K31/517
- IPC分类号： A61K31/517
摘要：
The present invention comprises a new class of compounds capable of modulating the c-kit receptor and, accordingly, useful for treatment of c-kit mediated diseases, including various inflammatory, fibrotic and/or mast cell mediated diseases such as mastocytosis. The compounds have a general Formula I wherein A0-3 and R1-6 are defined herein. The invention further comprises pharmaceutical compositions, methods for treatment of c-kit mediated diseases, and intermediates and processes useful for the preparation of compounds of the invention.
公开/授权文献
- US20100160312A1 Substituted Pyridone Compounds and Methods of Use 公开/授权日：2010-06-24
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