发明授权
- 专利标题： 6-amino-purin-8-one compounds
- 专利标题（中）： 6-氨基 - 嘌呤-8-酮化合物
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申请号： US12537392申请日： 2009-08-07
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公开(公告)号： US08067426B2公开(公告)日： 2011-11-29
- 发明人: Keith Biggadike , Diane Mary Coe , Xiao Qing Lewell , Charlotte Jane Mitchell , Stephen Allan Smith , Naimisha Trivedi
- 申请人： Keith Biggadike , Diane Mary Coe , Xiao Qing Lewell , Charlotte Jane Mitchell , Stephen Allan Smith , Naimisha Trivedi
- 申请人地址： US PA Philadelphia
- 专利权人： GlaxoSmithKline LLC
- 当前专利权人： GlaxoSmithKline LLC
- 当前专利权人地址： US PA Philadelphia
- 代理商 Kaitlyn L. Coulter
- 主分类号： C07D473/18
- IPC分类号： C07D473/18 ; A61K31/522 ; C07D473/40 ; C07D473/16 ; A61P37/08 ; A61P11/06
摘要：
Compounds of formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
公开/授权文献
- US20100075995A1 COMPOUNDS 公开/授权日：2010-03-25
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