发明授权
- 专利标题： Method for the separation of intermediates which may be used for the preparation of escitalopram
- 专利标题（中）： 用于分离可用于制备依他普仑的中间体的方法
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申请号： US12781026申请日： 2010-05-17
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公开(公告)号： US08067640B2公开(公告)日： 2011-11-29
- 发明人: Naoki Taoka , Takahisa Kato , Shogo Yamamoto , Takashi Yoshida , Toshihiro Takeda , Yasuyoshi Ueda , Hans Petersen , Robert Dancer , Haleh Ahmadian , Lars O. Lyngso
- 申请人： Naoki Taoka , Takahisa Kato , Shogo Yamamoto , Takashi Yoshida , Toshihiro Takeda , Yasuyoshi Ueda , Hans Petersen , Robert Dancer , Haleh Ahmadian , Lars O. Lyngso
- 申请人地址： DK Valby-Copenhagen
- 专利权人： H. Lundbeck A/S
- 当前专利权人： H. Lundbeck A/S
- 当前专利权人地址： DK Valby-Copenhagen
- 代理商 Stephen G. Kalinchak; Mary Catherine Di Nunzio
- 优先权： DK200201201 20020812
- 主分类号： C07C57/00
- IPC分类号： C07C57/00
摘要：
The present invention relates to a novel method for the preparation of diol intermediates having the formula (II) and/or the opposite enantiomer of an acylated diol having the formula (IV) useful for the preparation of escitalopram involving selective enzymatic acylation or deacylation.
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