发明授权
- 专利标题: Targeted modification of chromatin structure
- 专利标题(中): 靶向修饰染色质结构
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申请号: US12803927申请日: 2010-07-09
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公开(公告)号: US08071370B2公开(公告)日: 2011-12-06
- 发明人: Alan P. Wolffe , Trevor Collingwood , Philip D. Gregory , Andrew Snowden , Fyodor Urnov
- 申请人: Alan P. Wolffe , Elizabeth J. Wolffe, legal representative , Trevor Collingwood , Philip D. Gregory , Andrew Snowden , Fyodor Urnov
- 申请人地址: US CA Richmond
- 专利权人: Sangamo Biosciences, Inc.
- 当前专利权人: Sangamo Biosciences, Inc.
- 当前专利权人地址: US CA Richmond
- 代理机构: Robins & Pasternak LLP
- 代理商 Dahna S. Pasternak
- 主分类号: C07H17/00
- IPC分类号: C07H17/00 ; C07K14/00
摘要:
Methods and compositions for targeted modification of chromatin structure, within a region of interest in cellular chromatin, are provided. Such methods and compositions are useful for facilitating processes such as, for example, transcription and recombination, that require access of exogenous molecules to chromosomal DNA sequences.
公开/授权文献
- US20100323424A1 Targeted modification of chromatin structure 公开/授权日:2010-12-23
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