发明授权
- 专利标题： Compounds capable of affecting differentiation, proliferation, regeneration, plasticity and survival cells
- 专利标题（中）： 能够影响分化，增殖，再生，可塑性和存活细胞的化合物
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申请号： US12435043申请日： 2009-05-04
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公开(公告)号： US08071549B2公开(公告)日： 2011-12-06
- 发明人: Vladislav V Kiselyov , Galina Skladchikova , Vladimir Berezin , Elisabeth Bock
- 申请人： Vladislav V Kiselyov , Galina Skladchikova , Vladimir Berezin , Elisabeth Bock
- 代理商 Iver P. Cooper
- 优先权： DK200101228 20010817; DK200200667 20020502
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/78 ; C07K14/705
摘要：
The present invention relates to a compound comprising the third Immunoglobulin (Ig3) module, and/or the fourth Immunoglobulin (Ig4) module, and/or the fifth immunoglobulin (Ig5) module, and/or the first Fibronectin III (Fn3,1) module, and/or the second Fibronectin III (Fn3,2) module of neural cell adhesion molecule (NCAM), or a fragment, or a variant thereof, capable of interacting with an Fibroblast Growth Factor (FGF) receptor and/or Adenosine-Tri-Phosphate (ATP) and/or L1, and thereby the compounds are capable of inducing differentiation, modulating proliferation, stimulate regeneration, neuronal plasticity and/or survival of cells. Further, the present invention relates to a pharmaceutical composition comprising said compound, a process of producing a pharmaceutical composition and the use of said compound.
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