Invention Grant
US08071569B2 Oxidized heparin fractions and their use in inhibiting angiogenesis
有权
氧化肝素部分及其在抑制血管生成中的应用
- Patent Title: Oxidized heparin fractions and their use in inhibiting angiogenesis
- Patent Title (中): 氧化肝素部分及其在抑制血管生成中的应用
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Application No.: US13029584Application Date: 2011-02-17
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Publication No.: US08071569B2Publication Date: 2011-12-06
- Inventor: Shaker A. Mousa
- Applicant: Shaker A. Mousa
- Agency: Schmeiser, Olsen & Watts, LLP
- Main IPC: A61K31/727
- IPC: A61K31/727 ; C08B37/10 ; C07H11/00
Abstract:
The present invention relates to a heparin fraction comprising constituents having molecular weights of from about 2,000 to about 4,000 daltons, wherein from about 1% to about 100% of hydroxyl residues of the constituents are oxidized. The present invention also relates to methods of inhibiting angiogenesis and treating an angiogenesis-mediated disorder in a subject by administering a heparin fraction comprising constituents having molecular weights of from about 2,000 to about 30,000 daltons, wherein from about 1% to about 100% of hydroxyl residues of the constituents are oxidized. Another aspect of the present invention relates to compositions including the heparin fractions of the present invention.
Public/Granted literature
- US20110200673A1 OXIDIZED HEPARIN FRACTIONS AND THEIR USE IN INHIBITING ANGIOGENESIS Public/Granted day:2011-08-18
Information query
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