发明授权
US08071745B2 Polynucleotides encoding rod-derived cone viability factor (rdcvf) and methods of using the same
有权
编码棒衍生的锥形存活因子（rdcvf）的多核苷酸及其使用方法
- 专利标题： Polynucleotides encoding rod-derived cone viability factor (rdcvf) and methods of using the same
- 专利标题（中）： 编码棒衍生的锥形存活因子（rdcvf）的多核苷酸及其使用方法
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申请号： US11739734申请日： 2007-04-25
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公开(公告)号： US08071745B2公开(公告)日： 2011-12-06
- 发明人: Thierry Léveillard , José Alain Sahel , Saddek Mohand-Said , David Hicks
- 申请人： Thierry Léveillard , José Alain Sahel , Saddek Mohand-Said , David Hicks
- 申请人地址： CH Basel FR Strasbourg
- 专利权人： Novartis AG,Universite de Strasbourg
- 当前专利权人： Novartis AG,Universite de Strasbourg
- 当前专利权人地址： CH Basel FR Strasbourg
- 代理机构： Nelson Mullins Riley & Scarborough LLP
- 代理商 Jeanne M. DiGiorgio, Esq.; Jill Gorny Sloper, Esq.
- 优先权： FR0104712 20010406
- 主分类号： C07H19/00
- IPC分类号： C07H19/00 ; C07H21/00 ; C07H21/04 ; C12P21/00 ; C12P21/02 ; C12N15/00 ; C12N15/09 ; C12N15/10
摘要：
Disclosed are methods and compositions for early diagnosis, monitoring and treatment of retinal dystrophy, age-related macular degeneration, Bardet-Biedel syndrome, Bassen-kornzweig syndrome, best disease, choroidema, gyrate atrophy, congenital amourosis, refsun syndrome, stargardt disease and Usher syndrome. In particular, the invention relates to a protein, termed “Rdcvf1,” that is differentially transcribed and expressed in subjects suffering from retinal dystrophies and the like, such as retinal dystrophy and age-related macular degeneration compared with non-sufferers, antibodies which recognize this protein, and methods for diagnosing such conditions.
公开/授权文献
- US20090062188A1 Disease-Associated Protein 公开/授权日：2009-03-05
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