A separable and shape-changeable mouse includes a first housing, a second housing, a first connecting member and a second connecting member. The first housing includes a cursor signal generation unit, a first slant and a first connecting member. The second housing includes a receptacle for accommodating a battery therein, a second slant and a second connecting member. The first housing is combined with the second housing when the first connecting member is coupled with the second connecting member. By rotating the second housing with respect to the first housing, the shape of the mouse is changeable.