A mixing machine for agitating and mingling materials is disclosed. The mixing machine comprises a base and a driving device disposed on the base, and the driving device is connected to a rotary bracket and has a fixing portion with a container for receiving a mixture of materials mounted thereon, such that the mixture of materials may be agitated and mingled while the driving device drives the rotary bracket. A transmission device is disposed between the driving device and the rotary bracket, and the transmission device comprises a first spur gear, a second spur gear, and a bevel gear intermeshed which are successively intermeshed, wherein the first spur gear and the second spur gear are meshed together and fitted to parallel axles, the second spur gear and the bevel gear are meshed together, and the bevel gear connects to the fixing portion.